Advantages of the Biophilia Tracker X3 New 4D NLS Approach in BC Diagnosis

In the case of breast cancer (BC), the skeletal system is the most common location for distant metastases. 30-80% of breast cancer patients develop bone metastases during the disease process. Bone is first affected in 26-50% of patients with disseminated disease. According to available information, the most affected areas are: the spine and pelvis. At the same time, the risk of metastatic skeletal lesions was high in the case of the generalized stage of the disease; in the case of the disease stage I-II, the risk did not exceed 2.6%. This is why routine skeletal screening tests to detect metastases in patients with early disease without clinical symptoms of bone infection are considered unreasonable. Bone scans are often used as a screening method for patients with common diseases, or to confirm skeletal effects based on clinical data. However, due to the low specificity of this method, bone scan results are often inconclusive; this method is also not good at detecting lytic metastases. Radiological research methods, including traditional radiography and computed tomography, are used to specify received data. Computed tomography is more frequently chosen as long as conventional radiography is not sensitive and foci of destruction are detected only in the presence of substantial loss of bone material. Computed tomography allows separate visualization of cortical and trabecular bone and surrounding soft tissue, although it also does not provide early diagnosis of metastatic lesions in the bone marrow.


The advantages of the new 3D NLS method of the Biophilia Tracker X3 are: direct visualization of the bone marrow and the possibility to visualize its tumor infiltration before any skeletal alterations appear. Other considerable advantages of the 3D NLS approach are: usability, usability, and fast inspection. The latest technological achievements in this field have led to the creation of special modes of 3D visualization (4D organization, depth vision, fast vision) that provide excellent image quality.


The use of a unique ultra-scanning technique (existing only in the NLS method) with spectral entropy analysis allows to determine the morphological association of the formation based on its spectral similarity to the model process, to assess the metastatic lesions of bone, surrounding soft tissue and lymph nodes, to determine The presence and type of genetic aberrations in tumor subclones, which will ultimately determine the extent of surgical treatment.


The large database and powerful functions of the Biophilia Tracker X3 enable the advancement of various medical technologies.