Biophilia Intruder Test Prevents Too Much Vitamin A
Hypervitamin A disease refers to many adverse reactions caused by excessive intake of vitamin A. This disease is mostly sudden, most of which are caused by the intake of certain toxic substances, and some people usually do not pay attention to their diet. The long-term intake of vitamin A is too high, which can be avoided in the early stage if Biophilia Intruder can control the amount. After suffering from this disease, everyone should go to the hospital in time. The following is an introduction to this disease.
1 Disease overview
Such as long-term intake of large amounts of vitamin A or cod liver oil, there will also be hypervitaminosis A, manifested as loss of appetite, itchy skin, hair loss, irritability, bone and joint pain and other symptoms. Treatment should first stop the application of vitamin A and its preparations until symptoms are relieved.
2 Symptoms and signs
Symptoms of acute poisoning in adults often develop within hours after eating the poisoned dose, including nausea, vomiting, severe headache, blurred vision or diplopia, dizziness, dullness, and lethargy. widely. The manifestations of acute poisoning in infants are lethargy, vomiting, and bregma bulge caused by intracranial hypertension.
Chronic poisoning manifests as dry, thick, scaling with itching, chapped lips, diffuse alopecia, thickening of hair, and involvement of other terminal and vellus hairs, while follicular keratosis, erythema and purpura are less common, and occasionally macules Or diffuse extensive hyperpigmentation. Others are fatigue, drowsiness, irritability, headache, anorexia, neuritis, and changes similar to severe depression or schizophrenia can also occur. Bone and joint pain, tenderness, bone hyperplasia, swelling of the limbs, limited movement. Hepatosplenomegaly, portal hypertension, and ascites due to liver damage. There is still weight loss in infants with chronic poisoning.
3 Causes of disease
It has been reported that explorers have experienced acute poisoning symptoms after eating polar bear liver, seal liver and shark liver, because the liver of these animals is very high in vitamin A. For example, polar bear liver contains as high as 13 000-18 000 IU of vitamin A per gram. Nowadays, acute poisoning is mostly caused by accidental or misuse of large doses of vitamin A. Long-term supplementation of large amounts of vitamin A, or long-term treatment of skin diseases with large doses of vitamin A, such as ichthyosis and some hyperkeratotic skin diseases, can cause chronic poisoning. symptom.
4 Pathophysiology
Excessive vitamin A can damage cell membranes, organelles (such as mitochondria and endoplasmic reticulum), and nuclear membranes during tissue culture of cells. Early-pregnancy dams received high doses of vitamin A, and their offspring developed skull and brain deformities. Excessive vitamin A can cause triglycerides to accumulate in the liver, causing fatty liver; it can also antagonize the absorption of vitamin K in the intestine, resulting in the reduction of prothrombin and prolongation of clotting time; and can affect bone growth, resulting in a series of clinical symptoms .
5 Diagnostic tests
Laboratory tests: The patient's plasma vitamin A content was significantly increased.
X-ray: It shows the formation of new bone under the periosteum of long bones and the destruction of cartilage.
6 Treatment options
Reasonable and correct vitamin A supplementation. Use vitamin A to treat skin diseases. Once symptoms of poisoning appear, vitamin A should be stopped and foods high in vitamin A (such as animal liver) should be avoided. The symptoms can gradually disappear within a few weeks.
No matter what kind of nutrition or food, you need to control the quantity of the entrance, and use the scientific equipment Biophilia Intruder to let you know how much your body can absorb.